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Chromosomes can break! When they break, they get breakpoints. As a cell divides, during metaphase the chromosomes all line up in the center of the cell. Microtubules attach to the chromosomes and pull them apart, so half the DNA ends up in each daughter cell. Before the DNA gets pulled apart, the chromosomes are free [...]

I recently heard about a upcoming computer game called Cellcraft. The website isn’t updated much, but you can check it out at http://www.cellcraftgame.com/. It’s being made somewhere in North Carolina, but details on the web site are scarce. Anyway, the point of the project is to use a computer game to teach cell biology. This [...]

In my opinion, scientific writing is often poor. All too often, when I try to read a paper, I find myself having to re-read sentences or paragraphs before I finally understand the meaning. Much of the time, I can figure out ways to say the important points in fewer words with better structure. Of course, [...]

I was looking around to try to find a good short explanation of what allelic imbalance is, but was unable to find one. I eventually figured it out, and wanted to make a post to clarify this for future searchers: What is allelic imbalance? A difference in the expression between two alleles. Humans are diploid [...]